High fructose corn syrup may leave you hungry...
High fructose corn syrup is a sweetener produced using cornstarch.
It contains a mixture of glucose and fructose. Although high fructose
corn syrup can contain up to 90% fructose, most of the high fructose
corn syrup used in soft drinks contains 55% fructose [4].
According to records from the Department of Agriculture for the
period between 1967 and 2000, Americans eat an average of 132 calories
of high fructose corn syrup each day. The figure is closer to 300
calories for 2 out of 10 Americans [2].
High fructose corn syrup can raise both blood sugar and insulin
levels [5], both of which play a role in regulating hunger, but
it doesn't have the same impact as other forms of carbohydrate
such as glucose [6].
In other words, the calories in a soft drink
don't cause a feeling of fullness in the way that calories from
food do, promoting the "passive overconsumption" of calories and
sugar.
Publishing their findings in the Journal of Clinical Endocrinology
and Metabolism, researchers from the University of Pennsylvania
looked at the effect that high fructose corn syrup has on various
hormones that help to regulate hunger [1].
The researchers recruited 12 women of normal weight. On two different
days, the women ate the same three meals. After
each meal, they received a drink sweetened with
either glucose or high fructose corn syrup.
When subjects were given the drink sweetened with high fructose
corn syrup, levels of the hormones insulin and leptin were lower
than when they drank glucose. Rising insulin and leptin
levels trigger a feeling of being "full."
Following the high fructose corn syrup drink, levels of the hormone
ghrelin were also higher compared with the glucose drink.
A rising ghrelin level is linked with increased feelings of hunger.
"Soft drinks are the leading source of added sugar in the
American diet. They provide a large amount of excess calories
and no nutritional value," says Matthias Schulze, lead author
of a Harvard School of Public Health
study linking the regular consumption of soft drinks with weight
gain in young and middle-aged women [7].
Women in the study who increased their soft-drink consumption
from low to high during the study also increased their daily calorie
intake by approximately 360 per day. Women who cut
back on their consumption from high to low reduced their daily
calorie intake by nearly 320 calories.
Super-sized servings of burgers and fries head the list
of foods being blamed for America's obesity epidemic. The fact
that high fructose corn syrup doesn't have much effect on your
appetite means that the extra-large soda you drink to wash it all
down is probably just as important.
However, soft drinks most likely would have contributed
just as much to obesity even if they were still sweetened
with sucrose (soft drink manufacturers switched from sucrose
to high fructose corn syrup in the 1970's).
The contribution that soft drinks make to weight gain is due largely
to factors that increase their consumption, including massive soft-drink
advertising campaigns, the increase in serving sizes from 6.5 ounces
to bottles containing up to 64 ounces, as well as the increased
intake of soft drinks by children and adults at fast-food restaurants
(which sometimes offer free refills), cinemas, and convenience
stores.
While the
occasional soft drink won't make you fat or give you type II diabetes
and heart disease, an extra-large soda every day is not
a good idea.
Soft drink manufacturers have secret plans to come up with a low-carb,
low-fat, low-calorie, caffeine-free, additive-free cola. Rumor
has it they plan to call it water.
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Reference
1. Teff KL, Elliott SS, Tschop M, Kieffer TJ, Rader D, Heiman M,
Townsend RR, Keim NL, D'Alessio D, Havel PJ. (2004). Dietary fructose
reduces circulating insulin and leptin, attenuates postprandial
suppression of ghrelin, and increases triglycerides in women. Journal
of Clinical Endocrinology and Metabolism, 89, 2963-2972
2. Bray, G.A., Nielsen, S.J., & Popkin, B.M. (2004). Consumption
of high-fructose corn syrup in beverages may play a role in the
epidemic of obesity. American
Journal of Clinical Nutrition, 79, 537-543
3. Elliott, S.S., Keim, N.L., Stern, J.S., Teff, K., & Havel,
P.J. (2002). Fructose, weight gain, and the insulin resistance syndrome.
American
Journal of Clinical Nutrition, 76, 911-922
4. Bhosale, S.H., Rao, M.B., & Deshpande, V.V. (1996). Molecular
and industrial aspects of glucose isomerase. Microbiology
and Molecular Biology Reviews, 60, 280300
5. Akgun, S., & Ertel, N.H. (1981). Plasma glucose and insulin
after fructose an high-fructose corn syrup meals in subjects with
non-insulin-dependent diabetes mellitus. Diabetes
Care, 4, 464-467
6. Wellhoener, P., Fruehwald-Schultes, B., Kern, W., Dantz, D.,
Kerner, W., Born, J., Fehm, H.L., & Peters, A. (2000). Glucose
metabolism rather than insulin is a main determinant of leptin secretion
in humans. Journal
of Clinical Endocrinology and Metabolism, 85, 1267-1271
7. Schulze MB, Manson JE, Ludwig DS, Colditz GA, Stampfer MJ, Willett
WC, Hu FB. (2004). Sugar-sweetened beverages, weight gain, and incidence
of type 2 diabetes in young and middle-aged women. Journal
of the American Medical Association, 292, 927-934
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